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Cordarone, Pacerone
Antiarrhythmic • Class III antiarrhythmic
Blocks potassium, sodium, and calcium channels; also has beta-blocking properties
Drug Class
Antiarrhythmic
Subclass
Class III antiarrhythmic
Half-life
40-55 days
Time for plasma concentration to decrease by 50%
Protein Binding
96%
Fraction bound to plasma proteins
Therapeutic Index
Narrow
Margin between therapeutic and toxic doses