Haloperidol

Haldol

Antipsychotic • First-generation (typical) antipsychotic

QT RiskCNS Depressant

Half-life

14-26 hours

Protein Binding

92%

Metabolized By

CYP3A4, CYP2D6

External

Potent D2 dopamine receptor antagonist

Drug Class

Antipsychotic

Subclass

First-generation (typical) antipsychotic

Haldol

Half-life

14-26 hours

Time for plasma concentration to decrease by 50%

Protein Binding

92%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses