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Viagra, Revatio, Liqrev, Vybrique
PDE5 inhibitor • Phosphodiesterase-5 inhibitor
PremiumInhibits PDE5, increasing cGMP and causing smooth muscle relaxation
From the drug index — may include conditions studied rather than approved indications
2 curated · 1 major or contraindicated · select a row for management
| Interacting drug | Severity | Effect |
|---|---|---|
| rifampicin | major | Near-complete loss of PDE5 inhibitor efficacy (both for erectile dysfunction and pulmonary hypertension indications). |
| amiodarone | moderate | Excessive hypotension and QT prolongation risk. |
Additive hypotension and dizziness
Not recorded for Sildenafil. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Assembled from: drug index, curated drug database, curated interaction pairs.