Digoxin

Lanoxin

Cardiac glycoside • Cardiac glycoside

NTIQT Risk

Half-life

36-48 hours

Protein Binding

20-30%

Metabolized By

N/A

External

Inhibits Na+/K+-ATPase, increasing intracellular calcium and cardiac contractility

Drug Class

Cardiac glycoside

Subclass

Cardiac glycoside

Lanoxin

Half-life

36-48 hours

Time for plasma concentration to decrease by 50%

Protein Binding

20-30%

Fraction bound to plasma proteins

Therapeutic Index

Narrow

Margin between therapeutic and toxic doses