Lisinopril

Zestril, Prinivil

ACE Inhibitor • ACE inhibitor

Nephrotoxic

Half-life

12 hours

Protein Binding

25%

Metabolized By

N/A

External

Inhibits angiotensin-converting enzyme, reducing angiotensin II and aldosterone

Drug Class

ACE Inhibitor

Subclass

ACE inhibitor

ZestrilPrinivil

Half-life

12 hours

Time for plasma concentration to decrease by 50%

Protein Binding

25%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses