Lithium

Lithobid, Eskalith

Mood stabilizer • Alkali metal salt

NTIQT RiskCNS DepressantNephrotoxic

Half-life

18-36 hours

Protein Binding

Metabolized By

N/A

External

Modulates neurotransmitter release, intracellular signaling cascades, and gene expression

Drug Class

Mood stabilizer

Subclass

Alkali metal salt

LithobidEskalith

Half-life

18-36 hours

Time for plasma concentration to decrease by 50%

Protein Binding

Fraction bound to plasma proteins

Therapeutic Index

Narrow

Margin between therapeutic and toxic doses