Alprazolam

Xanax

Benzodiazepine • Short-acting benzodiazepine

CNS Depressant

Half-life

6-12 hours

Protein Binding

80%

Metabolized By

CYP3A4

External

Enhances GABA-A receptor activity, producing anxiolytic/sedative effects

Drug Class

Benzodiazepine

Subclass

Short-acting benzodiazepine

Xanax

Half-life

6-12 hours

Time for plasma concentration to decrease by 50%

Protein Binding

80%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses