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CellCept, Myfortic
Immunosuppressant • IMPDH inhibitor
Inhibits inosine monophosphate dehydrogenase, blocking purine synthesis in lymphocytes
Drug Class
Immunosuppressant
Subclass
IMPDH inhibitor
Half-life
17.9 hours (MPA)
Time for plasma concentration to decrease by 50%
Protein Binding
97%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses