Valacyclovir

Valtrex

Antiviral • Nucleoside analog prodrug

Nephrotoxic

Half-life

2.5-3.3 hours

Protein Binding

13-18%

Metabolized By

N/A

External

Prodrug of acyclovir with improved oral bioavailability

Drug Class

Antiviral

Subclass

Nucleoside analog prodrug

Valtrex

Half-life

2.5-3.3 hours

Time for plasma concentration to decrease by 50%

Protein Binding

13-18%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses