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Temazepam

Restoril

Uncategorized

Standard

Half-life

8-22 hours

Protein Binding

96%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Concomitant use with opioids may result in respiratory depression, coma, death

Clinical alerts

Boxed warning

1 boxed warning

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Enhances GABA-A receptor activity at benzodiazepine binding site

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Pruritus
·Dermatitis
·Otitis Externa
·Pierre Robin Sequence
·Brainstem Dysfunction

Interactions

No curated interaction pairs are recorded for Temazepam. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Drowsiness
Dizziness
Fatigue
Lethargy

Food, alcohol & herbal

Alcohol · major

Severe CNS and respiratory depression

Pharmacokinetics

Half-life: 8-22 hours
Protein binding: 96%

Pregnancy & lactation

Not recorded for Temazepam. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement

Temazepam

Restoril

Uncategorized

Standard

Half-life

8-22 hours

Protein Binding

96%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Concomitant use with opioids may result in respiratory depression, coma, death

Clinical alerts

Boxed warning

1 boxed warning

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Enhances GABA-A receptor activity at benzodiazepine binding site

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Pruritus
·Dermatitis
·Otitis Externa
·Pierre Robin Sequence
·Brainstem Dysfunction

Interactions

No curated interaction pairs are recorded for Temazepam. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Drowsiness
Dizziness
Fatigue
Lethargy

Food, alcohol & herbal

Alcohol · major

Severe CNS and respiratory depression

Pharmacokinetics

Half-life: 8-22 hours
Protein binding: 96%

Pregnancy & lactation

Not recorded for Temazepam. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement