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Saxagliptin

Kombiglyze, Qtern, Onglyza

Uncategorized

Standard

Half-life

2.5 hours (active metabolite: 3.1 hours)

Protein Binding

Negligible

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Inhibits DPP-4, prolonging GLP-1 and GIP activity

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Rectal Carcinoma
·Cardiovascular Events
·Type2 Diabetes
·Renal Disease
·Type 2 Diabetes Mellitus

Interactions

No curated interaction pairs are recorded for Saxagliptin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Upper respiratory infection
UTI
Headache

Food, alcohol & herbal

Alcohol · moderate

May increase hypoglycemia risk

Pharmacokinetics

Half-life: 2.5 hours (active metabolite: 3.1 hours)
Protein binding: Negligible
Metabolised by: CYP3A4

Pregnancy & lactation

Not recorded for Saxagliptin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement