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Ropinirole

Requip, Requip XL

Antiparkinson • Dopamine agonist (D2/D3 preferring)

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CNS Depressant

Half-life

6 hours

Protein Binding

40%

Metabolized By

CYP1A2

External

Drugs.com

Clinical alerts

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Directly stimulates D2/D3 dopamine receptors

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Idiopathic Parkinson's Disease
·Parkinson's Disease
·Parkinsonian Disorders
·Atypical Parkinson Disease
·Progressive Supranuclear Palsy

Interactions

No curated interaction pairs are recorded for Ropinirole. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Nausea
Dizziness
Somnolence
Syncope
Impulse control disorders
Sudden sleep onset

Food, alcohol & herbal

Food

Food reduces rate but not extent of absorption

Alcohol · moderate

Additive sedation

Pharmacokinetics

Half-life: 6 hours
Protein binding: 40%
Metabolised by: CYP1A2

Pregnancy & lactation

Not recorded for Ropinirole. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement