Ropinirole

Requip, Requip XL

Antiparkinson • Dopamine agonist (D2/D3 preferring)

CNS Depressant

Half-life

6 hours

Protein Binding

40%

Metabolized By

CYP1A2

External

Directly stimulates D2/D3 dopamine receptors

Drug Class

Antiparkinson

Subclass

Dopamine agonist (D2/D3 preferring)

RequipRequip XL

Half-life

6 hours

Time for plasma concentration to decrease by 50%

Protein Binding

40%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses