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  3. /Risperidone

Risperidone

Risperdal, Risperdal Consta, Perseris, Uzedy, Rykindo

Antipsychotic • Second-generation (atypical) antipsychotic

Premium
QT RiskCNS Depressant

Half-life

3-20 hours (varies by CYP2D6 status)

Protein Binding

Metabolized By

CYP2D6

External

Drugs.com

Mechanism of Action

Antagonizes dopamine D2 and serotonin 5-HT2A receptors

Indications(5)

Major Depression ModerateMajor Depression SevereMajor DepressionDepression - Major Depressive DisorderAnhedonia

Classification

Drug Class

Antipsychotic

Subclass

Second-generation (atypical) antipsychotic

Brand Names

RisperdalRisperdal ConstaPerserisUzedyRykindo

Key Properties

Half-life

3-20 hours (varies by CYP2D6 status)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Risperidone Drug Profile | PharmaGraphX