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Rifampin

Rifadin

Uncategorized

Standard

Half-life

3-4 hours

Protein Binding

80%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Hepatotoxic

Monitor liver function

Mechanism of action

Inhibits bacterial DNA-dependent RNA polymerase, blocking transcription

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Tuberculosis
·Tuberculosis, Pulmonary
·Tuberculosis, Lymph Node
·Mycobacterium Tuberculosis
·Obesity &Amp; Overweight

Interactions

No curated interaction pairs are recorded for Rifampin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Orange discoloration of body fluids
Hepatotoxicity
Nausea
Rash

Food, alcohol & herbal

Food

Take on empty stomach

Alcohol · major

Increased hepatotoxicity risk

Pharmacokinetics

Half-life: 3-4 hours
Protein binding: 80%
Induces: CYP3A4, CYP2C9, CYP2C19, CYP1A2, CYP2D6

Pregnancy & lactation

Not recorded for Rifampin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement