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Pregabalin

Lyrica, Lyrica CR, Bonqat

Anticonvulsant • GABA analog / Calcium channel modulator

Premium

CNS Depressant

Half-life

6.3 hours

Protein Binding

0%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Suicidal behavior and ideation
Drug abuse potential (Schedule V)

Clinical alerts

Boxed warning

2 boxed warnings

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Binds to alpha-2-delta subunit of voltage-gated calcium channels (more potent than gabapentin)

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Painful Diabetic Neuropathy (PDN)
·Peripheral Neuropathy With Type 2 Diabetes
·Vegan Diet
·Opioid Tapering
·Coronary Artery Bypass

Interactions

No curated interaction pairs are recorded for Pregabalin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Dizziness
Somnolence
Peripheral edema
Weight gain
Blurred vision

Food, alcohol & herbal

Alcohol · major

Additive CNS depression

Pharmacokinetics

Half-life: 6.3 hours
Protein binding: 0%

Pregnancy & lactation

Not recorded for Pregabalin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement

Pregabalin

Lyrica, Lyrica CR, Bonqat

Anticonvulsant • GABA analog / Calcium channel modulator

Premium

CNS Depressant

Half-life

6.3 hours

Protein Binding

0%

Metabolized By

N/A

External

Drugs.com

Boxed warning

Suicidal behavior and ideation
Drug abuse potential (Schedule V)

Clinical alerts

Boxed warning

2 boxed warnings

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Binds to alpha-2-delta subunit of voltage-gated calcium channels (more potent than gabapentin)

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Painful Diabetic Neuropathy (PDN)
·Peripheral Neuropathy With Type 2 Diabetes
·Vegan Diet
·Opioid Tapering
·Coronary Artery Bypass

Interactions

No curated interaction pairs are recorded for Pregabalin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Dizziness
Somnolence
Peripheral edema
Weight gain
Blurred vision

Food, alcohol & herbal

Alcohol · major

Additive CNS depression

Pharmacokinetics

Half-life: 6.3 hours
Protein binding: 0%

Pregnancy & lactation

Not recorded for Pregabalin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement