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Prednisone

Deltasone, Rayos

Corticosteroid • Glucocorticoid

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Half-life

2-3 hours (biological half-life 18-36 hours)

Protein Binding

70%

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of action

Binds to glucocorticoid receptors, suppressing inflammation and immune response

Interactions

No curated interaction pairs are recorded for Prednisone. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Weight gain
Insomnia
Mood changes
Hyperglycemia
Osteoporosis
Immunosuppression

Food, alcohol & herbal

Food

Take with food to reduce GI upset

Alcohol · moderate

Increased GI bleeding risk

Herbal

Licorice (moderate) — May increase corticosteroid effects and potassium loss

Pharmacokinetics

Half-life: 2-3 hours (biological half-life 18-36 hours)
Protein binding: 70%
Metabolised by: CYP3A4
Induces: CYP3A4

Pregnancy & lactation

Not recorded for Prednisone. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement