PharmaGraphX

Log in Get Started

Pravastatin

Pravachol

HMG • CoA reductase inhibitor (statin)

Standard

Half-life

1.5-2.5 hours

Protein Binding

43-55%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Hepatotoxic

Monitor liver function

Mechanism of action

Competitively inhibits HMG-CoA reductase, reducing cholesterol synthesis

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Radiation-associated Dysphagia
·Head &Amp; Neck Cancer
·Preeclampsia (PE)
·Intrauterine Growth Restriction (IUGR)
·Placental Insufficiency

Interactions

No curated interaction pairs are recorded for Pravastatin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Myalgia
Nausea
Headache
Elevated LFTs

Food, alcohol & herbal

Alcohol · moderate

Alcohol may increase hepatotoxicity risk

Pharmacokinetics

Half-life: 1.5-2.5 hours
Protein binding: 43-55%

Pregnancy & lactation

Not recorded for Pravastatin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement