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Protonix
Proton pump inhibitor • PPI
Irreversibly inhibits H+/K+ ATPase (proton pump) in gastric parietal cells
Drug Class
Proton pump inhibitor
Subclass
PPI
Half-life
1 hour
Time for plasma concentration to decrease by 50%
Protein Binding
98%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses