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Oxybutynin

Ditropan, Ditropan XL, Oxytrol, Gelnique

Urinary antispasmodic • Anticholinergic / Antimuscarinic

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CNS Depressant

Half-life

2-3 hours (IR); 12-13 hours (ER)

Protein Binding

>99%

Metabolized By

CYP3A4

External

Drugs.com

Clinical alerts

Anticholinergic

Adds to anticholinergic burden, particularly in older patients

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Antagonizes muscarinic receptors on bladder smooth muscle

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Interstitial Cystitis
·Levator Spasm
·Bladder Pain Syndrome
·Localized Prostate Cancer
·Postoperative Urinary Incontinence

Interactions

No curated interaction pairs are recorded for Oxybutynin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Dry mouth
Constipation
Dizziness
Blurred vision
Cognitive impairment

Food, alcohol & herbal

Alcohol · moderate

Additive CNS depression

Pharmacokinetics

Half-life: 2-3 hours (IR); 12-13 hours (ER)
Protein binding: >99%
Metabolised by: CYP3A4

Pregnancy & lactation

Not recorded for Oxybutynin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement