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Pamelor, Aventyl
Antidepressant • Tricyclic antidepressant (TCA)
Inhibits reuptake of norepinephrine and serotonin; also blocks muscarinic, histamine, and alpha-1 receptors
Drug Class
Antidepressant
Subclass
Tricyclic antidepressant (TCA)
Half-life
18-44 hours
Time for plasma concentration to decrease by 50%
Protein Binding
93-95%
Fraction bound to plasma proteins
Therapeutic Index
Narrow
Margin between therapeutic and toxic doses