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Nitroglycerin

Nitrostat, Nitro-Bid, Nitro-Dur, Minitran, Rectiv, Nitrolingual, Gonitro, NitroMist

Nitrate • Organic nitrate vasodilator

Premium

Half-life

1-4 minutes

Protein Binding

60%

Metabolized By

Hepatic first-pass

External

Drugs.com

Mechanism of action

Releases nitric oxide, causing venodilation and coronary vasodilation

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Achilles Tendon Repairs/Reconstructions
·Pilon Fracture of Tibia
·Tibial Plateau Fracture
·Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar)
·Calcaneus Fractures

Interactions

No curated interaction pairs are recorded for Nitroglycerin. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Headache
Hypotension
Dizziness
Flushing
Reflex tachycardia

Food, alcohol & herbal

Alcohol · major

Severe hypotension

Pharmacokinetics

Half-life: 1-4 minutes
Protein binding: 60%
Metabolised by: Hepatic first-pass

Pregnancy & lactation

Not recorded for Nitroglycerin. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement