PharmaGraphX

Log in Get Started

Nicardipine

Cardene

Uncategorized

Standard

Half-life

8-14 hours

Protein Binding

95%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Blocks L-type calcium channels; used IV for hypertensive emergencies

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Intracerebral Hemorrhage
·Stroke
·Hypertension
·Hypotensive Anesthesia
·Orthognathic Surgery

Interactions

No curated interaction pairs are recorded for Nicardipine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Headache
Flushing
Tachycardia
Pedal edema

Food, alcohol & herbal

Food

Food decreases absorption

Alcohol · moderate

Additive hypotension

Pharmacokinetics

Half-life: 8-14 hours
Protein binding: 95%
Metabolised by: CYP3A4
Inhibits: CYP3A4

Pregnancy & lactation

Not recorded for Nicardipine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement