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Naloxone

Zubsolv, Bunavail, Narcan, Kloxxado, Zimhi, Rextovy, Rezenopy, Suboxone

Uncategorized

Standard

Half-life

30-90 minutes

Protein Binding

45%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Competitive antagonist at mu, kappa, and delta opioid receptors

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Opioid Overdose
·Opioid-use Disorder
·Mental Health Conditions
·Healthy
·Opioid Use Disorder

Interactions

No curated interaction pairs are recorded for Naloxone. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Withdrawal symptoms (in opioid-dependent)
Nausea
Tachycardia
Hypertension

Pharmacokinetics

Half-life: 30-90 minutes
Protein binding: 45%

Pregnancy & lactation

Not recorded for Naloxone. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement