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Mesalamine

Delzicol, Canasa, Pentasa, Asacol, Rowasa, Lialda, Apriso

Uncategorized

Standard

Half-life

2-15 hours

Protein Binding

43%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Nephrotoxic

Monitor renal function; avoid other nephrotoxins where possible

Mechanism of action

Local anti-inflammatory in GI mucosa; inhibits COX and lipoxygenase pathways

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Ulcerative Colitis
·Inflammatory Bowel Diseases
·Ulcerative Colitis (UC)
·Colitis, Ulcerative
·Ul

Interactions

No curated interaction pairs are recorded for Mesalamine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Headache
Abdominal pain
Nausea
Diarrhea

Food, alcohol & herbal

Alcohol · minor

No significant interaction

Pharmacokinetics

Half-life: 2-15 hours
Protein binding: 43%

Pregnancy & lactation

Not recorded for Mesalamine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement