Loratadine

Claritin, Alavert, Wal-itin D, Loradamed, Wal-vert, Allerclear, Cleartime Indoor & Outdoor Allergies, Claritin-D, Tavist Non-Sedating, Alavert D, Wal-itin

Antihistamine • Second-generation H1 antihistamine

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Half-life

8.4 hours (active metabolite 28 hours)

Protein Binding

97-99%

Metabolized By

CYP3A4, CYP2D6

External

Drugs.com

Mechanism of action

Selective peripheral H1 receptor antagonist

Interactions

No curated interaction pairs are recorded for Loratadine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Headache
Drowsiness
Fatigue
Dry mouth

Food, alcohol & herbal

Alcohol · minor

No significant interaction

Pharmacokinetics

Half-life: 8.4 hours (active metabolite 28 hours)
Protein binding: 97-99%
Metabolised by: CYP3A4, CYP2D6

Pregnancy & lactation

Not recorded for Loratadine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement