Suicidality in children, adolescents, and young adults
Clinical alerts
Boxed warning
1 boxed warning
Bleeding risk
Additive with other antithrombotics and NSAIDs
Serotonergic
Serotonin syndrome risk when combined with other serotonergic drugs
Mechanism of action
Inhibits reuptake of serotonin and norepinephrine (preferentially NE)
Interactions
No curated interaction pairs are recorded for Levomilnacipran. This is not a statement that none exist — check a full interaction reference before combining.
Common adverse effects
Nausea
Constipation
Hyperhidrosis
Tachycardia
Food, alcohol & herbal
Alcohol · major
Additive CNS depression
Pharmacokinetics
Half-life
12 hours
Protein binding
22%
Metabolised by
CYP3A4
Pregnancy & lactation
Not recorded for Levomilnacipran. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Sources
Assembled from: drug index, curated drug database.
