Levetiracetam

Keppra, Keppra XR, Spritam

Antiepileptic • SV2A modulator

CNS Depressant

Half-life

6-8 hours

Protein Binding

<10%

Metabolized By

N/A

External

Binds to synaptic vesicle protein SV2A, modulating neurotransmitter release

Drug Class

Antiepileptic

Subclass

SV2A modulator

KeppraKeppra XRSpritam

Half-life

6-8 hours

Time for plasma concentration to decrease by 50%

Protein Binding

<10%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses