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Lacosamide

Motpoly, Vimpat

Biologic agent

Standard

Half-life

13 hours

Protein Binding

15%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

QT prolongation

Avoid combining with other QT-prolonging agents; check electrolytes

CNS depressant

Additive sedation with other CNS depressants and alcohol

Mechanism of action

Enhances slow inactivation of voltage-gated sodium channels

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Chronic Pain
·Chronic Pain Syndrome
·Chronic Pancreatitis
·Hyperalgesia
·Opioid Use Disorder

Interactions

No curated interaction pairs are recorded for Lacosamide. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Dizziness
Headache
Nausea
Diplopia

Food, alcohol & herbal

Alcohol · moderate

Additive CNS depression

Pharmacokinetics

Half-life: 13 hours
Protein binding: 15%
Metabolised by: CYP2C19

Pregnancy & lactation

Not recorded for Lacosamide. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement