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Labetalol

Trandate

Uncategorized

Standard

Half-life

5-8 hours

Protein Binding

50%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Hepatotoxic

Monitor liver function

Mechanism of action

Blocks alpha-1, beta-1, and beta-2 adrenergic receptors

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Hypotensive Anesthesia
·Orthognathic Surgery
·Thyroid Neoplasms
·Acute Ischemic Stroke
·Lactating Women on Select DOI

Interactions

No curated interaction pairs are recorded for Labetalol. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Orthostatic hypotension
Dizziness
Fatigue
Nausea

Food, alcohol & herbal

Food

Food increases bioavailability

Alcohol · moderate

Additive hypotension

Pharmacokinetics

Half-life: 5-8 hours
Protein binding: 50%
Metabolised by: CYP2D6

Pregnancy & lactation

Not recorded for Labetalol. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement