Fetal toxicity — women of childbearing potential should use contraception
Clinical alerts
Boxed warning
1 boxed warning
Mechanism of action
Selectively inhibits funny (If) current in sinoatrial node, reducing heart rate
Interactions
No curated interaction pairs are recorded for Ivabradine. This is not a statement that none exist — check a full interaction reference before combining.
Common adverse effects
Bradycardia
Phosphenes (visual brightness)
Atrial fibrillation
Food, alcohol & herbal
Food
Take with food
Alcohol · minor
No significant interaction
Herbal
St. John's Wort (major) — Reduces ivabradine levels via CYP3A4 induction
Pharmacokinetics
Half-life
6 hours
Protein binding
70%
Metabolised by
CYP3A4
Pregnancy & lactation
Not recorded for Ivabradine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.
Sources
Assembled from: drug index, curated drug database.
