Infliximab

Remicade, Inflectra, Renflexis

Biologic • TNF-alpha inhibitor

Hepatotoxic

Half-life

7.7-9.5 days

Protein Binding

N/A

Metabolized By

Proteolytic degradation

External

Chimeric (mouse/human) monoclonal antibody against TNF-alpha

Drug Class

Biologic

Subclass

TNF-alpha inhibitor

RemicadeInflectraRenflexis

Half-life

7.7-9.5 days

Time for plasma concentration to decrease by 50%

Protein Binding

N/A

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses