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  3. /Gentamicin

Gentamicin

Garamycin, Gentacalm, Genone, Motazol, Otomax, Mometamax, Garasol, Gentak, Pred-G, Mometavet, Mometamax Single, GentaVed

Antibiotic • Aminoglycoside

Premium
NTINephrotoxic

Half-life

2-3 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Binds to 30S ribosomal subunit, causing misreading of mRNA and bacterial death

Indications(5)

OsteomyelitisInterstitial CystitisLevator SpasmBladder Pain SyndromeSeptic Abortion

Classification

Drug Class

Antibiotic

Subclass

Aminoglycoside

Brand Names

GaramycinGentacalmGenoneMotazolOtomaxMometamaxGarasolGentakPred-GMometavetMometamax SingleGentaVed

Key Properties

Half-life

2-3 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Narrow

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Gentamicin Drug Profile | PharmaGraphX