Finasteride

Propecia, Proscar

Androgen inhibitor • 5-alpha reductase inhibitor

Half-life

5-6 hours (elderly: 8 hours)

Protein Binding

90%

Metabolized By

CYP3A4

External

Inhibits type II 5-alpha reductase, reducing DHT production

Drug Class

Androgen inhibitor

Subclass

5-alpha reductase inhibitor

PropeciaProscar

Half-life

5-6 hours (elderly: 8 hours)

Time for plasma concentration to decrease by 50%

Protein Binding

90%

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses