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  3. /Fexofenadine

Fexofenadine

Allegra, Wal-Fex, Wal-Fex D, Allegra-D

Antihistamine • Second-generation H1 antihistamine

Premium

Half-life

14.4 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Active metabolite of terfenadine; H1 antagonist with no CNS penetration

Indications(5)

HealthyPruritusProstatic Neoplasms, Castration-ResistantTranscatheter Aortic Valve ImplantationHealthy Volunteers

Classification

Drug Class

Antihistamine

Subclass

Second-generation H1 antihistamine

Brand Names

AllegraWal-FexWal-Fex DAllegra-D

Key Properties

Half-life

14.4 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Fexofenadine Drug Profile | PharmaGraphX