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Fexofenadine

Allegra, Wal-Fex, Wal-Fex D, Allegra-D

Antihistamine • Second-generation H1 antihistamine

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Half-life

14.4 hours

Protein Binding

60-70%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Active metabolite of terfenadine; H1 antagonist with no CNS penetration

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Healthy
·Pruritus
·Prostatic Neoplasms, Castration-Resistant
·Transcatheter Aortic Valve Implantation
·Healthy Volunteers

Interactions

No curated interaction pairs are recorded for Fexofenadine. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Headache
Back pain
Nausea

Food, alcohol & herbal

Food

Grapefruit, orange, and apple juice reduce absorption

Alcohol · minor

No significant interaction

Pharmacokinetics

Half-life: 14.4 hours
Protein binding: 60-70%

Pregnancy & lactation

Not recorded for Fexofenadine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement