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Fenofibrate

Tricor, Antara, Lipofen, Fenoglide, Trilipix, Fibricor

Uncategorized

Standard

Half-life

20 hours

Protein Binding

99%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Nephrotoxic

Monitor renal function; avoid other nephrotoxins where possible

Hepatotoxic

Monitor liver function

Mechanism of action

Activates PPARalpha, enhancing lipolysis and reducing triglyceride-rich particles

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Medulloblastoma Recurrent
·Ependymoma Recurrent
·ATRT Recurrent
·Rare CNS Tumor Recurrent
·Diabetic Nephropathies

Interactions

No curated interaction pairs are recorded for Fenofibrate. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Elevated LFTs
Dyspepsia
Myalgia
Rhinitis

Food, alcohol & herbal

Food

Take with food for optimal absorption

Alcohol · moderate

Alcohol may worsen hypertriglyceridemia

Pharmacokinetics

Half-life: 20 hours
Protein binding: 99%
Inhibits: CYP2C9

Pregnancy & lactation

Not recorded for Fenofibrate. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement