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  3. /Eszopiclone

Eszopiclone

Lunesta

Hypnotic • Non-benzodiazepine (Z-drug)

Premium
CNS Depressant

Half-life

6 hours

Protein Binding

Metabolized By

CYP3A4, CYP2E1

External

Drugs.com

Mechanism of Action

S-isomer of zopiclone; binds to GABA-A receptor

Indications(5)

InsomniaSleep ApneaObstructive Sleep ApneaComplex InsomniaHypertension

Classification

Drug Class

Hypnotic

Subclass

Non-benzodiazepine (Z-drug)

Brand Names

Lunesta

Key Properties

Half-life

6 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Eszopiclone Drug Profile | PharmaGraphX