Donepezil

Reversibly inhibits acetylcholinesterase, increasing ACh in the synapse

No curated interaction pairs are recorded for Donepezil. This is not a statement that none exist — check a full interaction reference before combining.

• Nausea
• Diarrhea
• Insomnia
• Muscle cramps
• Bradycardia

Half-life

70 hours

Protein binding

96%

Metabolised by

CYP2D6, CYP3A4

Not recorded for Donepezil. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.