Dobutamine

Predominantly beta-1 adrenergic agonist, increasing myocardial contractility with relatively little effect on heart rate or systemic vascular resistance at usual doses. Cleared by COMT, not by cytochrome P450.

• ·Sepsis - to Reduce Mortality in the Intensive Care Unit
• ·Septic Shock
• ·Shock, Septic
• ·Coronary Artery Disease
• ·Chest Pain

No curated interaction pairs are recorded for Dobutamine. This is not a statement that none exist — check a full interaction reference before combining.

• Tachycardia
• Ectopic beats
• Hypertension
• Angina
• Headache

Half-life

~2 minutes

Protein binding

Low

Not recorded for Dobutamine. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.