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  3. /Dexamethasone

Dexamethasone

Decadron, Tresaderm, Dexium, Maxitrol, Dexasone, Maxidex, Dexycu, Dextenza, Poly-Dex, Tobradex, Hemady, Ciprodex, Ozurdex

Corticosteroid • Glucocorticoid

Premium

Half-life

36-54 hours

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Potent glucocorticoid with minimal mineralocorticoid activity

Indications(5)

Multiple Myeloma, Newly DiagnosedMultiple MyelomaGastroesophageal JunctionGastroesophageal AdenocarcinomaEsophageal Neoplasms

Classification

Drug Class

Corticosteroid

Subclass

Glucocorticoid

Brand Names

DecadronTresadermDexiumMaxitrolDexasoneMaxidexDexycuDextenzaPoly-DexTobradexHemadyCiprodexOzurdex

Key Properties

Half-life

36-54 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Dexamethasone Drug Profile | PharmaGraphX