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  3. /Clindamycin

Clindamycin

Cleocin, Dalacin, ClindaCure, Clindacin, Zydaclin, Neuac, Onexton, Clinda-Guard, Xaciato, Cabtreo, Clindagel, Clindamax, Clindesse, Evoclin, Ziana, Cleocin-T, Acanya, Clintabs, ANTIROBE, Veltin

Antibiotic • Lincosamide

Premium
Hepatotoxic

Half-life

2.4 hours

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Binds to 50S ribosomal subunit, inhibiting bacterial protein synthesis

Indications(5)

Acne VulgarisSeptic AbortionDental ImplantsImmediate Dental Implant LoadingSurgical Site Infection

Classification

Drug Class

Antibiotic

Subclass

Lincosamide

Brand Names

CleocinDalacinClindaCureClindacinZydaclinNeuacOnextonClinda-GuardXaciatoCabtreoClindagelClindamaxClindesseEvoclinZianaCleocin-TAcanyaClintabsANTIROBEVeltin

Key Properties

Half-life

2.4 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Clindamycin Drug Profile | PharmaGraphX