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Celebrex
NSAID • Selective COX-2 inhibitor
Selectively inhibits COX-2, reducing inflammatory prostaglandins with less GI toxicity
Drug Class
NSAID
Subclass
Selective COX-2 inhibitor
Half-life
11 hours
Time for plasma concentration to decrease by 50%
Protein Binding
97%
Fraction bound to plasma proteins
Therapeutic Index
Wide
Margin between therapeutic and toxic doses