Skip to main content
PharmaGraphX
PharmaGraphX
Log inGet Started

Important Disclaimer

PharmaGraphX is a research and educational tool only. It is NOT intended for clinical decision-making, patient care, or medical advice. All drug information, calculations, interactions, and recommendations are for educational and research purposes only. Always consult qualified healthcare professionals, official drug labeling (FDA, TGA, EMA), and institutional guidelines before making any clinical decisions. The developers assume no liability for any decisions made based on information provided by this platform.

© 2026 PharmaGraphX. All rights reserved.

|

For research and educational purposes only. Not medical advice.

Help
  • Navigate between workspaces using the left sidebar.
  • Use the main chat to ask any pharmacology question.
  • Press G then H to quickly navigate home.
Navigation
HomeG H
PK/PD StudioG P
Interaction HubG A
Digital TwinG T
Molecular LabG M

Press Esc to close

  1. Home
  2. /Database
  3. /Carvedilol

Carvedilol

Coreg, Coreg CR

Beta blocker • Non-selective beta blocker with alpha-1 blocking

Premium

Half-life

7-10 hours

Protein Binding

Metabolized By

CYP2D6, CYP1A2, CYP2C9

External

Drugs.com

Mechanism of Action

Blocks beta-1, beta-2, and alpha-1 adrenergic receptors

Indications(5)

Liver CirrhosisDrug InteractionHER2-positive Breast CancerHER2+ Breast CancerPremature Ventricular Complexes

Classification

Drug Class

Beta blocker

Subclass

Non-selective beta blocker with alpha-1 blocking

Brand Names

CoregCoreg CR

Key Properties

Half-life

7-10 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Carvedilol Drug Profile | PharmaGraphX