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Calcitriol

Rocaltrol, Vectical

Uncategorized

Standard

Half-life

5-8 hours

Protein Binding

99.9%

Metabolized By

N/A

External

Drugs.com

Clinical alerts

Narrow therapeutic index

Small dose changes can cause toxicity or loss of effect

Mechanism of action

Active form of vitamin D; binds VDR receptor, promoting calcium/phosphorus absorption

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Malocclusion of Anterior Teeth
·Malocclusions
·Opioid Use Disorder
·Autosomal Dominant Hypocalcemia (ADH)
·X-linked Hypophosphatemia

Interactions

No curated interaction pairs are recorded for Calcitriol. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Hypercalcemia
Headache
Nausea
Weakness

Pharmacokinetics

Half-life: 5-8 hours
Protein binding: 99.9%
Metabolised by: CYP24A1, CYP3A4

Pregnancy & lactation

Not recorded for Calcitriol. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement