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  3. /Buspirone

Buspirone

Buspar

Anxiolytic • Serotonin 5-HT1A partial agonist

Premium
Serotoninergic

Half-life

2-3 hours

Protein Binding

Metabolized By

CYP3A4

External

Drugs.com

Mechanism of Action

Partial agonist at 5-HT1A receptors; no GABA activity

Classification

Drug Class

Anxiolytic

Subclass

Serotonin 5-HT1A partial agonist

Brand Names

Buspar

Key Properties

Half-life

2-3 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Buspirone Drug Profile | PharmaGraphX