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Bempedoic Acid

Nexletol, Nexlizet

Uncategorized

Standard

Half-life

21 hours

Protein Binding

99%

Metabolized By

N/A

External

Drugs.com

Mechanism of action

Inhibits ATP citrate lyase upstream of HMG-CoA reductase, reducing cholesterol synthesis in liver

Recorded indications

From the drug index — may include conditions studied rather than approved indications

·Acute Coronary Syndromes (ACS)
·Primary Hypercholesterolaemia
·Mixed Dyslipidemia
·Hypercholesterolemia
·Coronary Atherosclerosis

Interactions

No curated interaction pairs are recorded for Bempedoic Acid. This is not a statement that none exist — check a full interaction reference before combining.

Common adverse effects

Hyperuricemia
Muscle spasms
Back pain
Anemia

Pharmacokinetics

Half-life: 21 hours
Protein binding: 99%
Inhibits: OATP1B1

Pregnancy & lactation

Not recorded for Bempedoic Acid. Absence here means this database does not hold a category — not that the drug is safe in pregnancy or breastfeeding.

Sources

Assembled from: drug index, curated drug database.

Not a substitute for clinical judgement