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  3. /Baclofen

Baclofen

Lioresal, Gablofen, Ozobax, Lyvispah, Fleqsuvy

Muscle relaxant • GABA-B agonist

Premium
CNS Depressant

Half-life

3-4 hours

Protein Binding

Metabolized By

N/A

External

Drugs.com

Mechanism of Action

Activates GABA-B receptors, inhibiting spinal cord reflexes

Indications(5)

Rumination SyndromeBenzodiazepine DependenceHerpes ZosterPainHand Osteoarthritis

Classification

Drug Class

Muscle relaxant

Subclass

GABA-B agonist

Brand Names

LioresalGablofenOzobaxLyvispahFleqsuvy

Key Properties

Half-life

3-4 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Baclofen Drug Profile | PharmaGraphX