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  3. /Atomoxetine

Atomoxetine

Strattera

ADHD Treatment • Selective norepinephrine reuptake inhibitor

Premium
Hepatotoxic

Half-life

5 hours (extensive metabolizers); 21 hours (poor metabolizers)

Protein Binding

Metabolized By

CYP2D6

External

Drugs.com

Mechanism of Action

Selectively inhibits norepinephrine reuptake without significant dopamine effects

Indications(5)

Obstructive Sleep ApneaParkinson's Disease (PD)Freezing of GaitFreezing of Gait Symptoms in Parkinson DiseasePosttraumatic Stress Disorder With Attention Defic

Classification

Drug Class

ADHD Treatment

Subclass

Selective norepinephrine reuptake inhibitor

Brand Names

Strattera

Key Properties

Half-life

5 hours (extensive metabolizers); 21 hours (poor metabolizers)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Atomoxetine Drug Profile | PharmaGraphX