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  3. /Aspirin

Aspirin

Bayer, Ecotrin, Pamprin Max Formula, Stanback Headache Powder Reformulated Jan 2011, BC Arthritis, BC Original Formula, Arthriten Inflammatory Pain, Bromo Seltzer Antacid Pain Reliever, Exaprin, Backaid IPF, Ascomp, Excedrin PM Triple Action, Aspi-Cor, Durlaza, Alka-Seltzer, Yosprala, Aspergum, Anacin, Bayer Aspirin, Bufferin, Excedrin, Norgesic, Norwich Aspirin, P-A-C Analgesic, Saleto, St. Joseph Aspirin, Vanquish, Equagesic, Vazalore, Orphengesic, Exaprin Plus, Excedrin Back & Body, Anacin Advanced Headache Formula, Anacin Aspirin Regimen, Miniprin

Antiplatelet • COX inhibitor / NSAID

Premium
BleedingNephrotoxic

Half-life

15-20 minutes (dose-dependent)

Protein Binding

Metabolized By

CYP2C9

External

Drugs.com

Mechanism of Action

Irreversibly inhibits COX-1, preventing thromboxane A2 synthesis

Indications(5)

HER2-negative Breast CancerMetastatic Breast CancerMetaplastic Breast CarcinomaTNBC - Triple-Negative Breast CancerAcute Ischemic Stroke

Classification

Drug Class

Antiplatelet

Subclass

COX inhibitor / NSAID

Brand Names

BayerEcotrinPamprin Max FormulaStanback Headache Powder Reformulated Jan 2011BC ArthritisBC Original FormulaArthriten Inflammatory PainBromo Seltzer Antacid Pain RelieverExaprinBackaid IPFAscompExcedrin PM Triple ActionAspi-CorDurlazaAlka-SeltzerYospralaAspergumAnacinBayer AspirinBufferinExcedrinNorgesicNorwich AspirinP-A-C AnalgesicSaletoSt. Joseph AspirinVanquishEquagesicVazaloreOrphengesicExaprin PlusExcedrin Back & BodyAnacin Advanced Headache FormulaAnacin Aspirin RegimenMiniprin

Key Properties

Half-life

15-20 minutes (dose-dependent)

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Aspirin Drug Profile | PharmaGraphX