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  3. /Aripiprazole

Aripiprazole

Abilify, Abilify Maintena, Opipza

Antipsychotic • Second-generation (atypical) antipsychotic

Premium

Half-life

75-94 hours

Protein Binding

Metabolized By

CYP3A4, CYP2D6

External

Drugs.com

Mechanism of Action

Partial agonist at D2 and 5-HT1A receptors; antagonist at 5-HT2A receptors

Classification

Drug Class

Antipsychotic

Subclass

Second-generation (atypical) antipsychotic

Brand Names

AbilifyAbilify MaintenaOpipza

Key Properties

Half-life

75-94 hours

Time for plasma concentration to decrease by 50%

Protein Binding

—

Fraction bound to plasma proteins

Therapeutic Index

Wide

Margin between therapeutic and toxic doses

Not a substitute for clinical judgement
Aripiprazole Drug Profile | PharmaGraphX